Use of yacM and yqeJ, essential bacterial genes and polypeptides and their use

摘要

Disclosed are genes, termed "yacM" and "yqeJ," which are essential for survival for a wide range of bacteria, such as Streptococcus pneumoniae, Bacillus subtilis, and E. coli. These genes and the essential polypeptides they encode can be used to identify antibacterial agents for treating a broad spectrum of bacterial infections.