发明名称 |
ESTERS OF ACYL CARNITINES WITH LONG-CHAIN ALIPHATIC ALCOHOLSAND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME HAVING ANTIBACTERIAL ACTIVITY |
摘要 |
Esters of acyl L-carnitines of general formula (I) <IMG> wherein R is a straight or branched aryl group having 2 to 16 carbon atoms, in particular isobutyryl and isovaleryl; n is an integer comprised between 7 and 15, particularly 10; and, X- is the anion of a pharmacologically acceptable acid are endowed with potent antibacterial activity. Pharmaceutical compositions comprising an ester of formula (I) can be utilized in human therapy and in the veterinary field.
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申请公布号 |
CA2087085(C) |
申请公布日期 |
2003.12.16 |
申请号 |
CA19932087085 |
申请日期 |
1993.01.11 |
申请人 |
SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. |
发明人 |
SANTANIELLO, MOSE;TINTI, MARIA ORNELLA;MISITI, DOMENICO;FORESTA, PIERO |
分类号 |
A61K31/22;A61P31/04;C07C229/22;(IPC1-7):C07C229/22 |
主分类号 |
A61K31/22 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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