发明名称 Reagents for detection and purification of antibody fragments
摘要 An isolated B1 domain polypeptide of bacterial Protein G which binds a Fab fragment of an IgG but substantially does not bind a Fc fragment of an IgG. Methods for the detection and purification of IgG Fc antibody fragments and Fab antibody fragments using the isolated GB1 domain polypeptides are also disclosed.
申请公布号 US6663862(B1) 申请公布日期 2003.12.16
申请号 US19990326342 申请日期 1999.06.04
申请人 DUKE UNIVERSITY 发明人 HELLINGA HOMME W.;SLOAN DAVID J.
分类号 C07K14/31;C07K14/315;C07K16/06;(IPC1-7):A01N63/00;A61K39/395;A61K39/40;A61K39/42;A61K39/38 主分类号 C07K14/31
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