发明名称 |
Reagents for detection and purification of antibody fragments |
摘要 |
An isolated B1 domain polypeptide of bacterial Protein G which binds a Fab fragment of an IgG but substantially does not bind a Fc fragment of an IgG. Methods for the detection and purification of IgG Fc antibody fragments and Fab antibody fragments using the isolated GB1 domain polypeptides are also disclosed. |
申请公布号 |
US6663862(B1) |
申请公布日期 |
2003.12.16 |
申请号 |
US19990326342 |
申请日期 |
1999.06.04 |
申请人 |
DUKE UNIVERSITY |
发明人 |
HELLINGA HOMME W.;SLOAN DAVID J. |
分类号 |
C07K14/31;C07K14/315;C07K16/06;(IPC1-7):A01N63/00;A61K39/395;A61K39/40;A61K39/42;A61K39/38 |
主分类号 |
C07K14/31 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|