| 发明名称 |
CELL ADHESION INHIBITORS |
| 摘要 |
A cell adhesion inhibitor of the general formula: R 3 -L-L'-R 1 is disclosed. An inhibitor of the present invention interacts with VLA-4 molecules and inhibits VLA-4 dependent cell adhesion. Also disclosed are methods for preparing and using such a cell adhesion inhibitor, as well as pharmaceutical compositions containing the same. |
| 申请公布号 |
PL354063(A1) |
申请公布日期 |
2003.12.15 |
| 申请号 |
PL20000354063 |
申请日期 |
2000.08.14 |
| 申请人 |
BIOGEN,INC. |
发明人 |
LEE WEN-CHERNG;SCOTT DANIEL;CORNEBISE MARK;PETTER RUSSELL |
| 分类号 |
C07D307/24;A61K31/165;A61K31/17;A61K31/341;A61K31/343;A61K31/397;A61K31/40;A61K31/401;A61K31/4025;A61K31/4035;A61K31/407;A61K31/421;A61K31/427;A61K31/4406;A61K31/443;A61K31/4439;A61K31/445;A61K31/451;A61K31/4709;A61K31/5375;A61K31/575;A61K38/00;A61P1/04;A61P3/10;A61P11/00;A61P11/02;A61P11/06;A61P17/06;A61P19/02;A61P25/28;A61P27/14;A61P29/00;A61P31/04;A61P37/02;A61P37/08;A61P43/00;C07C233/51;C07C233/83;C07C311/20;C07D205/04;C07D207/16;C07D207/263;C07D209/46;C07D211/64;C07D211/96;C07D213/56;C07D263/04;C07D265/30;C07D307/81;C07D401/06;C07D401/08;C07D401/10;C07D401/12;C07D401/14;C07D403/12;C07D405/06;C07D405/12;C07D405/14;C07D409/06;C07D417/12;C07J9/00;C07K5/02;C07K5/06;C07K5/078 |
主分类号 |
C07D307/24 |
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