发明名称 |
IMMEDIATE RELEASE PHARMACEUTICAL FORMULATION |
摘要 |
According to the present invention there is provided an immediate release pharmaceutical formulation comprising, as active ingredient, a compound of formula (I), wherein R1 represents C1-2#191 alkyl substituted by one or more fluoro substituents;R2 represents hydrogen, hydroxy, methoxy or ethoxy; andn represents 0, 1 or 2;or a pharmaceutically acceptable salt thereof; and a pharmaceutically acceptable diluent or carrier; provided that when the activ e ingredient is other than in the form of a salt the formulation does not sole ly contain:.bullet. a solution of one active ingredient and water;.bullet. a solution of one active ingredient and dimethylsulphoxide; or.bullet. a solution of one active ingredient in a mixture of ethanol : PEG 660 12-hydro xy stearate : water 5:5:90; such formulations being of use for the treatment of a cardiovascular disorder.
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申请公布号 |
CA2485533(A1) |
申请公布日期 |
2003.12.11 |
申请号 |
CA20032485533 |
申请日期 |
2003.05.27 |
申请人 |
ASTRAZENECA AB |
发明人 |
THUNE, MIKAEL;SIGFRIDSSON, CARL-GUSTAF;MAGNUSSON, ANDERS;ALAMI ABRAHMSEN, SUSANNA;INGHARDT, TORD |
分类号 |
C07D205/04;A61K9/00;A61K9/08;A61K9/20;A61K31/397;A61K47/10;A61K47/12;A61K47/26;A61K47/40;A61P7/02;A61P9/00;A61P9/10;(IPC1-7):A61K9/00 |
主分类号 |
C07D205/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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