摘要 |
<p>Imidazolium compounds of formula (I); wherein: A¯ is an anion; R1, R2 and R3 are the same or different and are hydrogen, C1-C6 alkyl, aryl, fused aryl, or heteroaryl; or are substituted aryl, fused aryl or heteroaryl; X and Y are the same or different and are -CH2, -C=O, -CHOH, -C=S, or -C=NR6; R4 and R5 are the same or different and are aryl, substituted aryl, heteroaryl, or substituted heteroaryl; and R6 is aryl,C1-C6 alkyl, OH, C1-C6 alkoxy, or aryloxy.are useful as inhibitors of a chemokine receptor knows as CXCR3 and its equivalent chemokine receptors.</p> |