发明名称 NEW SALTS
摘要 There is provided pharmaceutically-acceptable acid addition salts of compounds of formula (I), wherein R<1> represents C1-2 alkyl substituted by one or more fluoro substituents; R<2> represents C1-2 alkyl; and n represents 0, 1 or 2, which salts are useful as prodrugs of competitive inhibitors of trypsin-like proteases, such as thrombin, and thus, in particular, in the treatment of conditions where inhibition of thrombin is required (e.g. thrombosis) or as anticoagulants.
申请公布号 WO03101957(A1) 申请公布日期 2003.12.11
申请号 WO2003SE00859 申请日期 2003.05.27
申请人 ASTRAZENECA AB;AHLQVIST, MATTI;BOHLIN, MARTIN;INGHARDT, TORD;LUNDBLAD, ANITA;SIGFRIDSSON, CARL-GUSTAF 发明人 AHLQVIST, MATTI;BOHLIN, MARTIN;INGHARDT, TORD;LUNDBLAD, ANITA;SIGFRIDSSON, CARL-GUSTAF
分类号 C07D205/04;A61K;A61K31/396;A61K31/397;A61P7/02;A61P9/04;A61P9/08;A61P9/10;A61P11/00;A61P25/28;A61P29/00;A61P31/04;A61P43/00;C07D;(IPC1-7):C07D205/04 主分类号 C07D205/04
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