COMBINATION THERAPIES FOR IMMUNE MEDIATED DISEASES

摘要

The current invention provides for methods of immunotherapy using a combination of epitope-specific and cytokine or anticytokine immunotherapy. The method provides for modulation of pathogenic immune response and includes the identification of molecules comprising specific epitopes involved in a particular disease state of interest, administration of the epitope-specific molecule in conjunction with the cytokine or anticytokine, and downstream modification of the administration of the cytokine/anticytokine relative to the administration of the epitope-specific molecule. Figure 1 is a graph showing the effects on mean arthritis scores calculated into four groups following induction of Adjuvant Arthritis.