发明名称 A HUMAN CELL ASSAY TO DETERMINE EFFECT OF SAMPLE COMPOUNDS ON COL2 ENHANCER EXPRESSION
摘要 <p>This invention relates to human chondrocyte activity (growth)/differentiation/production of extracellular matrix) and to the effect of Sox9transcription factor and Colt enhancer as a measure for such activity. It also relates to a chimeric cell and assay utilizing such cell useful in predicting the effect of sample compounds on chondrocyte activity as measured by Sox9 and Colt expression/activity.</p>
申请公布号 WO2003102130(P1) 申请公布日期 2003.12.11
申请号 IB2003002256 申请日期 2003.05.26
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