发明名称 |
METHOD FOR ANALYSIS OF TRANSCRIPTION VARIATIONS IN A SET OF GENES |
摘要 |
The invention relates to a method for analysing the variations in concentration of RNA messengers obtained by transcription of a set of genes comprising the following steps:- measure the concentration of RNA messengers for each of the genes in the so-called reference cells and in test cells and report the results in a reference list and a test list, calculate a variation value for each gene which is a measure of the difference in concentration of m-RNA for said gene between the reference list and the test list, calculate a normalised variation value for each gene such that the cumulative frequency distribution of a sub-set of normalised variation values corresponding to genes has similar or identical m-RNA concentrations whatever the sub-set under consideration and identification of the genes with m-RNA concentration variations significantly different to normalised variation values.
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申请公布号 |
WO03102849(A1) |
申请公布日期 |
2003.12.11 |
申请号 |
WO2003FR01655 |
申请日期 |
2003.06.02 |
申请人 |
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE;BELLIS, MICHEL |
发明人 |
BELLIS, MICHEL |
分类号 |
C12Q1/68;G06F19/20;(IPC1-7):G06F19/00 |
主分类号 |
C12Q1/68 |
代理机构 |
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