发明名称 MODIFIED RELEASE PHARMACEUTICAL FORMULATION
摘要 A modified release pharmaceutical composition comprising, as active ingredient, a compound of formula (I), wherein R1 represents C1-2#191 alkyl substituted by one or more fluoro substituents;R2 represents hydrogen, hydroxy, methoxy or ethoxy; andn represents 0, 1 or 2;or a pharmaceutically acceptable salt thereof; and a pharmaceutically acceptable diluent or carrie r; provided that the formulation may only contain iota-carrageenan and a neutra l gelling polymer when the compound of formula (I) is in the form of a salt; such formulations being of use for the treatment of a cardiovascular disorde r.
申请公布号 CA2485535(A1) 申请公布日期 2003.12.11
申请号 CA20032485535 申请日期 2003.05.27
申请人 ASTRAZENECA AB 发明人 MAGNUSSON, ANDERS;THUNE, MIKAEL
分类号 C07D205/04;A61K9/00;A61K9/06;A61K9/20;A61K9/22;A61K9/52;A61K31/397;A61K47/36;A61P1/18;A61P7/02;A61P7/10;A61P9/00;A61P9/04;A61P9/10;A61P11/00;A61P25/28;A61P29/00;A61P31/04;A61P39/00;A61P41/00;A61P43/00;(IPC1-7):A61K9/00 主分类号 C07D205/04
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