| 摘要 |
<p>Provided herein is a method of magnetic resonance imaging (MRI) for in vivo mapping of concentration of a target metal ion in at least one tissue using a contrast agent selectively sensitive for the amount of target metal ion where the contrast agent itself contains a non-hydrogen imaging nucleus. Also provided a method of diagnosing a disease state and of monitoring the efficacy of a therapeutic regimen to treat the disease state using the magnetic resonance imaging methods.</p> |
