发明名称 |
Method for producing antimicrobial protein and fusion protein |
摘要 |
A basic antimicrobial protein is activated by a partner protein having an isoelectric point below pH 7 and a chaperon function, by expressing an antimicrobially inactive fusion protein between the basic antimicrobial protein and the partner protein, recovering the fusion protein and separating the two proteins from each other. In such manner, an advantageous mass expression system of the basic antimicrobial protein having an appropriate disulfide bond as an active type is realized at lost cost.
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申请公布号 |
US2003228654(A1) |
申请公布日期 |
2003.12.11 |
申请号 |
US20010864169 |
申请日期 |
2001.05.25 |
申请人 |
KABUSHIKI KAISHA TOYOTA CHUO KENKYUSHO |
发明人 |
IMAEDA TAKAO;YAMADA YUKIO;HIRAI MASANA;SHIMAMURA TAKASHI;KOHDA KATSUNORI;MURAMOTO NOBUHIKO |
分类号 |
C07K14/415;C07K14/435;C12N1/21;C12N15/62;C12P21/02;(IPC1-7):C07K14/47;C07H21/04;C12N15/74 |
主分类号 |
C07K14/415 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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