Use of tryptophan metabolites as pharmaceutical agents

摘要

The present invention relates to the use of tryptophan metabolites as pharmaceutical agents. <??>Kynurenine, N-formylkynurenine, anthranilic acid, quinolinic acid, 3-hydroxykynurenine, and / or 3-hydroxyanthranilic acid can be employed for the treatment of any disease, which requires immunosuppressive treatment such as the inhibition of T cell response. <??>Examples of such diseases are immunologically caused recurrent abortions, autoimmune or rheumatic diseases. Furthermore, they can be used for suppression of rejection in the case of cell, tissue, or organ transplantations.