发明名称 |
THE ENZYME-MEDIATED SYNTHESIS OF PEPTIDOMIMETICS |
摘要 |
<p>A process for the preparation of a compound of formula (1)comprises reacting compounds of formulae (2) and (3)in the presence of an enzyme, wherein A is a thiol-protecting group, B, C and D are each the same or different organic groups of up to 30 C atoms, optionally functionalized at any position, provided that neither a primary amine nor a primary amide is present, and X is a group that can be displaced by NH2.</p> |
申请公布号 |
EP1123410(B1) |
申请公布日期 |
2003.12.10 |
申请号 |
EP19990950932 |
申请日期 |
1999.10.20 |
申请人 |
DARWIN DISCOVERY LIMITED |
发明人 |
HOLT, KAREN;TAYLOR, STEPHEN, J. C.;TIFFIN, PETER, DAVID |
分类号 |
C12P13/02;C07K5/06;C12P21/02;C12P41/00;(IPC1-7):C12P41/00;C07K5/08;C12N9/54 |
主分类号 |
C12P13/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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