| 摘要 |
In a method for autologous myocardial implantation treatment, a donor area of a patient containing healthy skeletal muscle is located. Myocyte micro granules are retrieved from the donor area using a retrieval device and either directly implanted into an implantation area of the patient's myocardium, or they are transferred to an implantation device and then implanted. No intervening cell culturing is performed between myocyte micro granule retrieval and implantation. A retrieval device that may be used to retrieve the myocyte micro granules from the donor area includes one or more extraction probes each having a distal tip adapted to be inserted into the skeletal muscle of the donor area. The retrieval device further includes a retrieval system that causes each distal tip to withdraw a myocyte micro granule upon removal thereof from the donor area. An implantation device that may be used to implant the myocyte micro granules includes a tubular body, an injection tip on the body that is adapted to enter the damaged area and deliver the micro granules, and a plunger within the body for pushing the micro granules through the injection tip. In one configuration of the implantation device that is especially adapted for implantation according to an epicardial approach, the device includes a handle extending laterally from the body for grasping by a medical practitioner when the injection tip is placed in the beating myocardium. In another configuration of the implantation device that is especially adapted for implantation according to a transfemoral approach, the device includes a retractable screen system for blocking myocyte micro granules from leaving the myocardium during implantation.
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