Modified protein derived from protein kinase N

摘要

A object of the present invention is to provide a peptide inhibiting tumorigenesis or metastasis. The present invention is a peptide or derivatives thereof comprising a modified amino acid sequence of Protein Kinase N having the activated Rho protein binding activity and not having protein kinase activity, and a peptide or derivatives thereof comprising a modified amino acid sequence of Protein Kinase N inhibiting the protein kinase activity of Protein Kinase N or the enhancement of the activity and not having protein kinase activity.