| 发明名称 |
Heteropolycyclic compounds and their use as metabotropic glutamate receptor antagonists |
| 摘要 |
The present invention provides compounds and pharmaceutical compositions that act as antagonists at metabotropic glutamate receptors, and that are useful for treating neurological diseases and disorders. Methods of preparing the compounds also are disclosed.
|
| 申请公布号 |
US6660753(B2) |
申请公布日期 |
2003.12.09 |
| 申请号 |
US20020076618 |
申请日期 |
2002.02.19 |
| 申请人 |
NPS PHARMACEUTICALS, INC. |
发明人 |
VAN WAGENEN BRADFORD;STORMANN THOMAS M.;MOE SCOTT T.;SHEEHAN SUSAN M.;MCLEOD DONALD A.;SMITH DARYL L.;ISAAC METHVIN BENJAMIN;SLASSI ABDELMALIK |
| 分类号 |
C07D213/55;C07D213/75;C07D213/78;C07D213/79;C07D401/04;C07D405/04;C07D405/14;C07D413/04;C07D413/14;C07D417/04;C07D521/00;(IPC1-7):C07D401/02;A61K31/44 |
主分类号 |
C07D213/55 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
