发明名称 |
alpha-O-linked glycoconjugates, methods of preparation and uses thereof |
摘要 |
The present invention provides novel alpha-O-linked glycoconjugates such as alpha-O-linked glycopeptides, as well convergent methods for synthesis thereof. The general preparative approach is exemplified by the synthesis of the mucin motif commonly found on epithelial tumor cell surfaces. The present invention further provides compositions and methods of treating cancer using the alpha-O-linked glycoconjugates.
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申请公布号 |
US6660714(B1) |
申请公布日期 |
2003.12.09 |
申请号 |
US19980083776 |
申请日期 |
1998.03.25 |
申请人 |
SLOAN KETTERING INSTITUTE FOR CANCER RESEARCH |
发明人 |
DANISHEFSKY SAMUEL J.;SAMES DALIBOR;HINTERMANN SAMUEL;CHEN XIAO-TAO;SCHWARTZ JACOB B.;GLUNZ PETER;RAGUPATHI GOVINDASWAMI;LIVINGSTON PHILIP O.;KUDUK SCOTT;WILLIAMS LAWRENCE |
分类号 |
C07H3/06;A61K38/00;A61K39/00;A61K39/39;A61K45/00;A61P35/00;C07H15/04;C07K7/00;C07K9/00;C07K14/47;(IPC1-7):A01N37/18 |
主分类号 |
C07H3/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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