ENHANCING THE EFFICACY OF REVERSE TRANSCRIPTASE AND DNA POLYMERASE INHIBITORS (NUCLEOSIDE ANALOGS) USING PNP INHIBITORS AND/OR 2'-DEOXYGUANOSINE AND/OR PRODRUG THEREOF

摘要

The efficacy of reverse transcriptase and DNA polymerase inhibitors (nucleoside analogs) in a mammalian host is enhanced by administering an effective amount of PNP inhibitor of prodrug of PNP inhibitor and/or an effective amounts of 2'-deoxyguanosine and/or prodrugs thereof.