发明名称 Use of trifunctional bispecific and trispecific antibodies for the treatment of malignant ascites
摘要 The invention describes the use of a pharmaceutical preparation containing a trifunctional bispecific and/or trispecific having the following properties: a) binding to a T cell; b) binding to at least an antigen on a tumor cell associated with malignant ascites and/or pleural effusion; c) binding, by its Fc portion (in the case of bispecific antibodies) or by a third specificity (in the case of trispecific antibodies), to Fc receptor-positive cells for the destruction of the tumor cells in the treatment of malignant ascites and/or pleural effusion.
申请公布号 US2003223999(A1) 申请公布日期 2003.12.04
申请号 US20030378218 申请日期 2003.03.03
申请人 LINDHOFER HORST 发明人 LINDHOFER HORST
分类号 A61K39/00;A61K39/395;A61P35/00;C07K16/28;C07K16/30;C07K16/32;(IPC1-7):A61K39/395 主分类号 A61K39/00
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