DIAGNOSTICS AND THERAPEUTICS FOR DISEASES ASSOCIATED WITH ARGININE VASOPRESSIN RECEPTOR 3 (AVPR3)

摘要

The invention provides a human AVPR3 which is associated with the hematological diseases, cardiovascular diseases, disorders of the peripheral and central nervous system, genitourinary diseases, cancer and respiratory diseases. The invention also provides assays for the identification of compounds useful in the treatment or prevention of hematological diseases, cardiovascular diseases, disorders of the peripheral and central nervous system, genitourinary diseases, cancer and respiratory diseases. The invention also features compounds which bind to and/or activate or inhibit the activity of AVPR3 as well as pharmaceutical compositions comprising such compounds.