发明名称 |
FORMULATIONS OF ERYTHROMYCIN DERIVATIVES WITH IMPROVED BIOAVAILABILITY |
摘要 |
The present invention describes a pharmaceutical composition for controlled release of Erythromycin derivatives, which provides better bioavailability by releasing the active agent with modified crystal characteristics immediately as well as in a controlled manner over a desired period for the treatment of various types of infections. The composition in the form of matrix tablet comprises of erythromycin derivative with modified crystal characteristics which exhibits better solubility and hence imparts improved bioavailability with negligible or no gastric side effects as compared to those immediate release compositions. More particularly, the said invention relates to pharmaceutical compositions of roxithromycin. |
申请公布号 |
WO03099197(A2) |
申请公布日期 |
2003.12.04 |
申请号 |
WO2002IN00183 |
申请日期 |
2002.09.05 |
申请人 |
J.B. CHEMICALS & PHARMACEUTICALS LTD. |
发明人 |
DOSHI, MADHUKANT, MANSUKHLAL;JOSHI, MILIND, DATTATRAYA;MEHTA, BHARAT, PRAVINCHANDRA |
分类号 |
A61K9/14;A61K9/20;A61K31/7048 |
主分类号 |
A61K9/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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