发明名称 |
PEG-CONJUGATES OF HGT-NK4 |
摘要 |
A conjugate comprising an N-terminal fragment of hepatocyte growth factor (HGF/SF) consisting of the hairpin domain and the four kringle regions of the alpha -chain and a polyethylene glycol group having an overall molecular weight of from about 20 to 40 kDA, has improved properties is a useful therapeutic agent for tumor treatment. |
申请公布号 |
WO02074344(A3) |
申请公布日期 |
2003.12.04 |
申请号 |
WO2002EP01837 |
申请日期 |
2002.02.21 |
申请人 |
F. HOFFMANN-LA ROCHE AG |
发明人 |
BRANDT, MICHAEL;PAPADIMITRIOU, APOLLON |
分类号 |
A61K47/48;A61P35/00;C07K14/475 |
主分类号 |
A61K47/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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