发明名称 PEG-CONJUGATES OF HGT-NK4
摘要 A conjugate comprising an N-terminal fragment of hepatocyte growth factor (HGF/SF) consisting of the hairpin domain and the four kringle regions of the alpha -chain and a polyethylene glycol group having an overall molecular weight of from about 20 to 40 kDA, has improved properties is a useful therapeutic agent for tumor treatment.
申请公布号 WO02074344(A3) 申请公布日期 2003.12.04
申请号 WO2002EP01837 申请日期 2002.02.21
申请人 F. HOFFMANN-LA ROCHE AG 发明人 BRANDT, MICHAEL;PAPADIMITRIOU, APOLLON
分类号 A61K47/48;A61P35/00;C07K14/475 主分类号 A61K47/48
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