发明名称 |
(2S)-2-ETHYLPHENYLPROPIONIC ACID DERIVATIVE |
摘要 |
A novel (2S)-2-ethylphenylpropionic acid derivative and an addition salt thereof. They combine as a ligand with a human peroxisome proliferator- activated receptor (PPAR).alpha. to activate it. They are effective in lipid depression, arteriosclerotic inhibition, antiobesity, blood sugar depression , etc. Also provided is a medicinal composition of either of these. The (2S)-2 - ethylphenylpropionic acid derivative is represented by the general formula (1): (1) wherein R1 represents halogeno or trifluoromethyl; R2 represents halogeno or trifluoromethyl when R3 represents hydrogen, and represents hydrogen, halogeno, or trifluoromethyl when R3 represents halogeno or trifluoromethyl; and R3 represents hydrogen, halogeno, or trifluoromethyl.</ SDOAB>
|
申请公布号 |
CA2487450(A1) |
申请公布日期 |
2003.12.04 |
申请号 |
CA20032487450 |
申请日期 |
2003.05.26 |
申请人 |
KYORIN PHARMACEUTICAL CO., LTD. |
发明人 |
HORI, WATARU;ISOGAI,SHIGEKI;ASANO, JUN |
分类号 |
A61P3/04;A61P3/06;A61P3/10;A61P9/10;A61P43/00;C07C235/60;C07D209/48;C07D263/26;(IPC1-7):C07C235/60;A61K31/192;A61K31/421 |
主分类号 |
A61P3/04 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|