METHOD FOR PREPARING AN INTERACTIVE COMPOUND OF AN ANILIDE DERIVATIVE WITH A POROUS SUPPORT BY SUPERCRITICAL FLUID

摘要

The invention concerns a method for preparing interactive compounds of an anilide derivative with a porous support, characterized in that it comprises the following steps: (a) mixing the anilide derivative generated by supercritical fluid and the specific amount of porous support, (b) carrying out a step of molecular diffusion by contacting in static mode a supercritical fluid with the mixture obtained at step (a) for the time required to improve the dissolution in an aqueous medium of the mixture obtained at step (a), (c) washing the interaction compound obtained at step (b) with a flux of supercritical fluid, (d) recuperating the particles of the resulting interaction compound. The invention also concerns a compound obtainable by said method and its use as medicine.