| 摘要 |
A microanalytical device is provided for conducting multiple chemical and/or biochemical reactions and analyzing multiple sample fluids in parallel using minute volumes of reaction or sample fluid. The devices comprises a well plate with an integrated microfluidic system containing processing compartments such as microcavities, microchannels and the like, that are in fluid communication with electrospray emitters. The novel microanalytical device can be used in a variety of chemical and biochemical contexts, including mass spectroscopy, chromatographic, electrophoretic and electrochromatographic separations, screening and diagnostics, and chemical and biochemical synthesis. The devices may be formed from a material that is thermally and chemically stable and resistant to biofouling, significantly reducing electroosmotic flow and unwanted adsorption of solute.
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