发明名称 |
LIPOSOME PREPARATION |
摘要 |
The present invention provides a liposome preparation containing oxaliplatin and derivatized with a hydrophilic polymer, as well as a pharmaceutical composition for treatment of tumor comprising the liposome preparation. The liposome preparation according to the present invention is characterized in that it is derivatized with a ligand. The ligand is preferably transferrin. In accordance with the invention, the uptake of a pharmaceutical agent in the liposome into tumor cells can be enhanced through transferrin receptors expressed on the surface of the tumor cells.
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申请公布号 |
CA2409795(A1) |
申请公布日期 |
2003.12.03 |
申请号 |
CA20022409795 |
申请日期 |
2002.10.25 |
申请人 |
MEBIOPHARM CO., LTD. |
发明人 |
ERIGUCHI, MASAZUMI;YANAGIE, HIRONOBU;MARUYAMA, KAZUO;FUJISAWA, TADASHI |
分类号 |
A61K9/127;A61K31/282;A61K31/555;A61K39/395;A61K47/22;A61K47/24;A61K47/26;A61K47/34;A61K47/36;A61K47/42;A61K47/48;A61P35/00;(IPC1-7):A61K33/24 |
主分类号 |
A61K9/127 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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