发明名称 LIPOSOME PREPARATION
摘要 The present invention provides a liposome preparation containing oxaliplatin and derivatized with a hydrophilic polymer, as well as a pharmaceutical composition for treatment of tumor comprising the liposome preparation. The liposome preparation according to the present invention is characterized in that it is derivatized with a ligand. The ligand is preferably transferrin. In accordance with the invention, the uptake of a pharmaceutical agent in the liposome into tumor cells can be enhanced through transferrin receptors expressed on the surface of the tumor cells.
申请公布号 CA2409795(A1) 申请公布日期 2003.12.03
申请号 CA20022409795 申请日期 2002.10.25
申请人 MEBIOPHARM CO., LTD. 发明人 ERIGUCHI, MASAZUMI;YANAGIE, HIRONOBU;MARUYAMA, KAZUO;FUJISAWA, TADASHI
分类号 A61K9/127;A61K31/282;A61K31/555;A61K39/395;A61K47/22;A61K47/24;A61K47/26;A61K47/34;A61K47/36;A61K47/42;A61K47/48;A61P35/00;(IPC1-7):A61K33/24 主分类号 A61K9/127
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