摘要 |
1,260,697. Cephalosporin sulphoxides. ELI LILLY & CO. 24 July, 1969 [3 Oct., 1968], No. 37342/69. Heading C2A. A process for the oxidation of a cephalosporin to a cephalosporin sulphoxide comprises treating the cephalosporin with at least one equivalent of an oxidizing agent at a temperature in the range of - 50‹ to + 100‹ C., the oxidizing agent being selected from inorganic peracids having a reduction potential of at least + 1À5 volts and containing only non-metallic elements, organic carboxylic peracids, and mixtures of hydrogen peroxide and an acid having a dissociation constant of at least 10<SP>-5</SP>. |