| 摘要 |
<p>Cpds. of formula (I) R' = OH opt. esterified or etherified Y = H, OH opt. esterified. Thymolytic, suprarenal inhibitory and anti-inflammatory activity. 0.3-3 mg/kg. orally or 1-10 mg/kg. s.c. in rats markedly inhibits foreign-body-induced granuloma. The thymolytic effect is 10 times greater than the anti-inflammatory effect when a 21-acetate is admin. orally. The 21-pivalate corresponding to the 21-acetate has a similar anti-inflammatory activity but the thymolytic activity is less than the anti-inflamm. activity. May be used in animal foods.</p> |
