MICROORGANISM ACTINOPLANES TEICHOMYCETICUS MSL 1510 PRODUCING TEICOPLANIN

摘要

PURPOSE: A microorganism Actinoplanes teichomyceticus MSL 1510 producing teicoplanin is provided. The microorganism produces a larger quantity of teicoplanin than a mother microorganism. CONSTITUTION: A microorganism Actinoplanes teichomyceticus MSL 1510(KCTC 10200BP) producing teicoplanin is produced by inoculating Actinoplanes teichomyceticus(KCTC 8926P) on Bennett's agar medium, culturing the medium at 28 deg. C for 7 days, filtering the cultured medium with glass fiber, diluting filtered spores in 50mM tris-malate buffer solution, irradiating 0.2 Mrad gamma ray to the spore solution and culturing the solution, isolating colonies grown, culturing isolated colonies on an agar medium containing Bacillus subtilis at 37 deg. C for 18 hours, and selecting a strain showing the excellent teicoplanin producing activity.