| 发明名称 |
METODO PARA IDENTIFICAR AGENTES ACTIVOS CONTRA O VHC UTILIZANDO AS COORDENADAS ESTRUTURAIS DA PROTEASE DO VIRUS DA HEPATITE C |
| 摘要 |
The present invention relates to compositions and crystals of a hepatitis C virus protease in complex with its viral cofactor. This invention also relates to methods of using the structure coordinates of hepatitis C virus protease in complex with a synthetic NS4A to solve the structure of similar or homologous proteins or protein complexes. |
| 申请公布号 |
PT1118619(E) |
申请公布日期 |
2003.11.28 |
| 申请号 |
PT20010101009T |
申请日期 |
1997.09.12 |
| 申请人 |
VERTEX PHARMACEUTICALS INCORPORATED |
发明人 |
JOSEPH L. KIM;KURT A. MORGENSTERN;CHAO LIN;TED FOX;JOHN A. THOMSON |
| 分类号 |
C07K1/00;C07K14/18;C07K19/00;C30B7/00;G01N33/576;G06F17/30;G06F19/16 |
主分类号 |
C07K1/00 |
| 代理机构 |
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代理人 |
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