CAPPING ENZYME OF FLAVIVIRUS AND UTILIZATION OF THIS PROTEIN IN A PROCESS TO TEST DRUGS WITH ANTIVIRAL PROPERTIES
摘要
The present invention concerns an isolated and purified polypeptide capable of acting as a guanylyltransferase and methyltransferase comprising capping enzyme of flavivirus (CEF). The present invention also concerns the use of such polypeptide to identify biologically active molecule which can be used in the treatment or the prevention of diseases resulting from Flavivirus infection.
申请公布号
WO02097075(B1)
申请公布日期
2003.11.27
申请号
WO2002IB02908
申请日期
2002.05.31
申请人
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS);ROMETTE, JEAN-LOUIS;BENARROCHE, DELPHINE;CANARD, BRUNO;EGLOFF, MARIE-PIERRE