发明名称 METHODS FOR THE PREVENTION AND/OR THE TREATMENT OF NEUROLOGICAL DISORDERS
摘要 The present invention relates to the use of substrates of an UDP-glucuronosyltransferase (UGT) and salts thereof, for the prevention and /or the treatment of neurological disorders. In preferred embodiment, the present invention relates to the use of substrates of at least an UDP-glucuronosyltransferase (UGT) expressed in brain and salts thereof, for the prevention and /or the treatment of neurological disorders. It further relates to the use of said substrates, and salts thereof, for preventing and/or treating glutamate cytotoxicity, and more specifically of glutamate induced neurological disorders. Additionally, it concerns the use of said substrates, and salts thereof, for making drugs exerting an inhibitory effect on the release of glutamate.
申请公布号 WO03097024(A1) 申请公布日期 2003.11.27
申请号 WO2003EP05186 申请日期 2003.05.16
申请人 FAUST PHARMACEUTICALS;NEUVILLE, PASCAL 发明人 NEUVILLE, PASCAL
分类号 A61K45/00;A61K31/00;A61K31/045;A61K31/05;A61K31/06;A61K31/136;A61K31/165;A61K31/167;A61K31/192;A61K31/196;A61K31/201;A61K31/203;A61K31/216;A61K31/235;A61K31/357;A61K31/37;A61K31/40;A61K31/402;A61K31/403;A61K31/4045;A61K31/4178;A61K31/423;A61K31/485;A61K31/5513;A61K31/7048;A61K31/7072;A61K31/7076;A61K38/00;A61P5/00;A61P5/48;A61P9/00;A61P9/10;A61P21/00;A61P25/00;A61P25/04;A61P25/08;A61P25/14;A61P25/16;A61P25/28;A61P25/30;A61P27/02;A61P43/00;(IPC1-7):A61K31/00;A61K31/551 主分类号 A61K45/00
代理机构 代理人
主权项
地址