摘要 |
The invention provides compounds of formula (I), wherein R<1 >represents C1-4 alkoxy optionally substituted by one or more fluorine atoms; R<2 >represents H or C1-6 alkoxy optionally substituted by one or more fluorine atoms; R<3 >represents one or more groups independently selected from H, halogen, C1-4 alkoxy and CF3; in addition, R<2 >and one R<3 >group may together represent -OCH2-, the methylene group being attached to the ortho-position of the pendant phenyl ring; R<4 >represents a 4-, 5- or 6-membered heterocyclic ring containing 1 or 2 heteroatoms selected from N, O and S, the ring being optionally fused to a benzene ring or a 5- or 6-membered heterocyclic ring containing 1 or 2 heteroatoms selected from N, O and S, the ring system as a whole being optionally substituted; X represents CH or N; and L is absent or represents a cyclic group or an open chain group; and the pharmaceutically acceptable salts thereof. The compounds of formula (I) are useful in the treatment of inter alia benign prostatic hyperplasia.
|