PREPARATION OF 4-(4-FLUOROPHENYL)-N-SUBSTITUTEDNIPECOTINATE ESTERS
摘要
A process for the industrial scale manufacture of 4-(4-fluorophenyl)-N-alkylnipecotinate esters by the addition of 4-fluorophenylmagnesium halide in tetrahydrofuran to 3,4-unsaturated-3-piperidine esters.
申请公布号
WO03097599(A1)
申请公布日期
2003.11.27
申请号
WO2003CA00700
申请日期
2003.05.14
申请人
BRANTFORD CHEMICALS INC.;REY, ALLAN, W.;MURTHY, KESHAVA, K., S.;RADATUS, BRUNO;ZHAO, YAJUN;NISH, TANIA, E.
发明人
REY, ALLAN, W.;MURTHY, KESHAVA, K., S.;RADATUS, BRUNO;ZHAO, YAJUN;NISH, TANIA, E.
