发明名称 |
Fermentative preparation process for and crystal forms of cytostatics |
摘要 |
The invention relates to a new process for concentrating epothilones in culture media, a new process for the production of epothilones, a new process for separating epothilones A and B and a new strain obtained by mutagenesis for the production of epothilones, as well as aspects related thereto. New crystal forms of epothilone B are also described.
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申请公布号 |
US2003220379(A1) |
申请公布日期 |
2003.11.27 |
申请号 |
US20030459762 |
申请日期 |
2003.06.12 |
申请人 |
HOFMANN HANS;MAHNKE MARION;MEMMERT KLAUS;PETERSEN FRANK;SCHUPP THOMAS;KUSTERS ERNST;MUTZ MICHAEL |
发明人 |
HOFMANN HANS;MAHNKE MARION;MEMMERT KLAUS;PETERSEN FRANK;SCHUPP THOMAS;KUSTERS ERNST;MUTZ MICHAEL |
分类号 |
A61K31/427;A61P35/00;A61P35/04;A61P43/00;B01D15/08;C07D493/04;C12N1/14;C12P;C12P17/16;C12P17/18;C12R1/01;C12R1/645;(IPC1-7):A61K31/427;C12N1/16 |
主分类号 |
A61K31/427 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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