发明名称 METHODS AND COMPOSITIONS USING 3-(4-AMINO-1-OXO-1,3-DIHYDROISOINDOL-2-YL)-PIPERIDINE-2,6-DIONE FOR TREATMENT AND MANAGEMENT OF HEAD AND NECK CANCER
摘要 <p>Methods of treating, preventing and/or managing cancer as well as and diseases and disorders associated with, or characterized by, undesired angiogenesis are disclosed. Specific methods encompass the administration of an immunomodulatory compound alone or in combination with a second active ingredient. The invention further relates to methods of reducing or avoiding adverse side effects associated with chemotherapy, radiation therapy, hormonal therapy, biological therapy or immunotherapy which comprise the administration of an immunomodulatory compound. Pharmaceutical compositions, single unit dosage forms, and kits suitable for use in methods of the invention are also disclosed. In a specific embodiment, the cancer is lymphoma.</p>
申请公布号 CA2752124(A1) 申请公布日期 2003.11.27
申请号 CA20032752124 申请日期 2003.05.16
申请人 CELGENE CORPORATION 发明人 ZELDIS, JEROME B.
分类号 A61K31/454;A61K45/00;A61K31/00;A61K31/198;A61K31/40;A61K31/4035;A61K31/425;A61K31/445;A61K31/515;A61K31/573;A61K35/12;A61K35/14;A61K35/28;A61K45/06;A61K51/00;A61P1/04;A61P1/16;A61P3/06;A61P3/10;A61P7/02;A61P7/06;A61P9/00;A61P9/04;A61P9/10;A61P9/14;A61P11/00;A61P11/06;A61P11/16;A61P17/00;A61P17/02;A61P17/06;A61P17/10;A61P17/12;A61P19/02;A61P19/08;A61P19/10;A61P25/00;A61P27/02;A61P27/06;A61P27/10;A61P27/14;A61P29/00;A61P31/00;A61P31/04;A61P31/08;A61P31/10;A61P31/12;A61P31/18;A61P31/22;A61P33/00;A61P33/02;A61P33/06;A61P35/00;A61P35/02;A61P35/04;A61P37/00;A61P37/02;A61P37/06;A61P37/08;A61P41/00;A61P43/00;C07D209/46;C07D401/04;C07J5/00 主分类号 A61K31/454
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