| 发明名称 |
METHODS USING A COMBINATION OF A 3-HETEROARYL-2-INDOLINONE AND A CYCLOOXYGENASE-2 INHIBITOR FOR THE TREATMENT OF NEOPLASIA |
| 摘要 |
The present invention provides methods and compositions useful for treatment or prevention of neoplasia by administering a combination comprising a 3-heteroaryl-2-indolinone compound and a COX-2 selective inhibitor. Further provided are compositions, pharmaceutical compositions, and kits for treatment and prevention of neoplasia.
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| 申请公布号 |
WO03097044(A1) |
申请公布日期 |
2003.11.27 |
| 申请号 |
WO2003US15582 |
申请日期 |
2003.05.15 |
| 申请人 |
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发明人 |
MASFERRER, JAIME, L.;CHERRINGTON, JULIE, M.;LEAHY, KATHLEEN, M.;ZWEIFEL, BEN, S. |
| 分类号 |
C07D403/06;A61K31/135;A61K31/341;A61K31/404;A61K31/415;A61K31/4178;A61K31/4192;A61K31/4196;A61K31/42;A61K31/422;A61K31/4245;A61K31/427;A61K31/445;A61K31/454;A61K31/496;A61K31/50;A61K31/501;A61K31/505;A61K31/506;A61K31/5377;A61K31/675;A61K33/24;A61K41/00;A61K45/00;A61K45/06;A61P35/00;C07D209/34;C07D405/06;C07D409/06;C07D413/06;C07D417/06;(IPC1-7):A61K31/404;A61K31/537 |
主分类号 |
C07D403/06 |
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