SERINE HYDROXYMETHYLTRANSFERASE AS A TARGET FOR HERBICIDES

摘要

The invention relates to serine hydroxymethyltransferase (E.C. 2.1.2.1) as a target for herbicides and to nucleic acid sequences that code for a polypeptide with the biological activity of serine hydroxymethyltransferase, the absence of which causes retarded growth and chlorotic leaves. Said nucleic acid sequences include the nucleic acid sequence SEQ ID No:3, in addition to functional equivalents of the aforementioned nucleic acid sequence, or the nucleic acid sequence SEQ ID NO:7, in addition to functional equivalents of the aforementioned nucleic acid sequence. The invention also relates to the use of the aforementioned nucleic acid sequences, functional analogues of SEQ ID NO:3 or SEQ ID NO: 7 or polypeptides coded by one of the aforementioned nucleic acid sequences in a method for identifying compounds with a herbicidal action, which inhibit serine hydroxymethyltransferase, in addition to the use of the compounds identified by said method as herbicides.