PROCESS FOR PREPARING (R)-3,4-EPOXY-1-BUTANOL

摘要

The present invention relates to a novel process for preparing (R)-3,4-epoxy-1-butanol in particular, a process for preparing (R)-3,4-epoxy-1-butanol with relatively high yield and in a cost-effective manner, wherein (S)-3-alkyl or arylsulfonyloxy-butyrolactone used as a starting material is reduced under a mild condition to give 2-alkyl or arylsulfonyloxy-1,4-butanediol as an intermediate, and the intermediate is then epoxidized in the presence of a base to invert a chiral center.