This invention provides the identification of a truncation polym orphism of the mdr1 gene that is linked to ivermectin sen sitivity in subjects, such as collies. Also provided are methods for detecting drug transport sensibility in a subject, and animal models and in vitro cell systems using cells from animals having an mdr1 truncation.
申请公布号
WO02057499(A3)
申请公布日期
2003.11.27
申请号
WO2002US00868
申请日期
2002.01.10
申请人
WASHINGTON STATE UNIVERSITY RESEARCH FOUNDATION;MEALEY, KATRINA, L.;BENTJEN, STEVEN, A.
