发明名称 USE OF ACE INHIBITORS FOR REDUCING TYPE 2 DIABETES IN HIGH RISK PATIENTS
摘要 The present invention relates to the use of an angiotensin-converting enzyme inhibitor, such as ramipril, to reduce or prevent Type 2 diabetes in high risk patients. The present invention also relates the use of an angiotensin-converting enzyme inhibitor, such as ramipril, to reduce the decline of beta-cell function, increase islet blood flow, lower aldosterone secretion, lower renal potassium wasting, increase pancreatic beta-cell perfusion, reduce insulin resistance in skeletal muscles, and increase insulin-mediated glucose disposal and uptake by skeletal muscles.
申请公布号 WO03032965(A3) 申请公布日期 2003.11.27
申请号 WO2002US33213 申请日期 2002.10.17
申请人 KING PHARMACEUTICALS RESEARCH AND DEVELOPMENT, INC;YUSUF, SALIM 发明人 YUSUF, SALIM
分类号 A61K45/00;A61K31/00;A61K31/38;A61K31/403;A61K38/55;A61P1/18;A61P3/10;A61P3/12;A61P5/42;A61P5/50;A61P9/00;A61P43/00 主分类号 A61K45/00
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