STATINS (HMG-COA REDUCTASE INHIBITORS) AS A NOVEL TYPE OF IMMUNOMODULATOR, IMMUNSUPPRESSOR AND ANTI-INFLAMMATORY AGENT

摘要

The present invention relates to methods of causing MHC-class II or CD40 mediated immunomodulation, immunosuppression and anti-inflammatory action, in a subject suffering from or susceptible of suffering from a condition involving inappropriate immune response, which comprises administering to the subject at least one statin in an amount effective to modulate MHC class II or CD40 expression in the subject.