| 摘要 |
This invention relates to methods of signal amplification in nucleic acid hybridization reactions without the use of direct amplification of the target sequence. More particularly, it relates to methods of detecting target nucleic acids in samples such that detection is accomplished via probe-target and target-target hybridization. In one aspect, the present invention relates to methods of detecting genomic target nucleic acids such that the signal is amplified via formation of target-probe complexes.
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