发明名称 METHOD FOR IDENTIFYING TARGET EPITOPES OF THE T CELL MEDIATED IMMUNE RESPONSE AND FOR ASSAYING EPITOPE-SPECIFIC T CELLS
摘要 The invention relates to a method for assaying epitope-specific T cells and target epitopes of reactive T cells. The present invention further relates to vectors, comprising a first promoter that can be specifically induced in antigen-presenting cells by the epitope-specific contact with a T cell, a nucleic acid functionally linked with said first promoter and encoding a marker gene, a second promoter that is constitutive in antigen-presenting cells, and a nucleic acid that is functionally linked with said second promoter. The present invention further relates to antigen-presenting cells that are transduced with the vectors according to the invention.
申请公布号 WO03046212(A3) 申请公布日期 2003.11.27
申请号 WO2002DE04270 申请日期 2002.11.20
申请人 DEML, LUDWIG 发明人 DEML, LUDWIG
分类号 C07K14/705;C12N15/10;C12N15/85;G01N33/50;G01N33/68 主分类号 C07K14/705
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