发明名称 SUBSTITUTED QUINOLONE CARBOXYLIC ACIDS, THEIR DERIVATIVES, SITE OF ACTION, AND USES THEREOF
摘要 Substituted quinolone carboxylic acids and their derivatives are described. These compounds modulate the effect of .gamma.-aminobutyric acid (GABA) via a novel site on the GABAA receptor complex in a therapeutically relevant fashi on and may be used to ameliorate CNS disorders amenable to modulation of the GABAA receptor complex.
申请公布号 CA2484308(A1) 申请公布日期 2003.11.27
申请号 CA20032484308 申请日期 2003.05.12
申请人 THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 发明人 HOGENKAMP, DERK J.;JOHNSTONE, TIMOTHY B.C.;GEE, KELVIN W.
分类号 A61K31/47;A61K31/4709;A61P21/02;A61P25/00;A61P25/02;A61P25/06;A61P25/08;A61P25/18;A61P25/20;A61P25/22;A61P25/24;A61P25/28;A61P25/30;A61P25/36;A61P29/00;A61P43/00;C07D215/56;C07D401/12;(IPC1-7):C07D215/38;C07D215/16;C07D215/20 主分类号 A61K31/47
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