发明名称 |
Synthetic hepatitis C genes |
摘要 |
The present invention relates to polynucleotides comprising a DNA sequence encoding an HCV protein and fragments thereof that contain codons optimized for expression in a vertebrate host. Uses of the polynucleotides include eliciting an immune response specifically recognizing HCV.
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申请公布号 |
US6653125(B2) |
申请公布日期 |
2003.11.25 |
申请号 |
US20000194949 |
申请日期 |
2000.02.17 |
申请人 |
MERCK & CO., INC. |
发明人 |
DONNELLY JOHN J.;LIU MARGARET A.;SHIVER JOHN W.;FU TONG-MING |
分类号 |
C12N15/09;A61K31/7072;A61K31/711;A61K38/21;A61K39/00;A61K48/00;A61P31/20;A61P37/04;C07K14/18;C12R1/92;(IPC1-7):C12N15/79 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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