发明名称 Amphipatic polycarboxylic chelates and complexes with paramagnetic metals as MRI contrast agents
摘要 Substituted polycarboxylic ligand molecules and corresponding metal complexes of said ligands, preferably paramagnetic metals complexes for generating responses in the field of magnetic resonance imaging (MRI) The paramagnetic complexes of the polycarboxylic ligands possess advantageous tensioactive properties and are useful as MRI contrast media in formulations for investigating the blood pool.
申请公布号 US6652834(B2) 申请公布日期 2003.11.25
申请号 US20010014358 申请日期 2001.12.14
申请人 BRACCO INTERNATIONAL B.V. 发明人 ANELLI PIER LUCIO;LATTUADA LUCIANO;UGGERI FULVIO;LUX GIOVANNA;SERLETI MICHELE;GABELLINI MILENA;TOURNIER HERVE
分类号 A61K49/00;A61K49/06;A61K49/18;C07C229/16;C07C229/76;C07C233/47;C07C237/08;C07C237/10;C07C237/12;C07D257/02;C07F9/09;C07J41/00;(IPC1-7):C07C233/07 主分类号 A61K49/00
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