发明名称 |
Amphipatic polycarboxylic chelates and complexes with paramagnetic metals as MRI contrast agents |
摘要 |
Substituted polycarboxylic ligand molecules and corresponding metal complexes of said ligands, preferably paramagnetic metals complexes for generating responses in the field of magnetic resonance imaging (MRI) The paramagnetic complexes of the polycarboxylic ligands possess advantageous tensioactive properties and are useful as MRI contrast media in formulations for investigating the blood pool.
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申请公布号 |
US6652834(B2) |
申请公布日期 |
2003.11.25 |
申请号 |
US20010014358 |
申请日期 |
2001.12.14 |
申请人 |
BRACCO INTERNATIONAL B.V. |
发明人 |
ANELLI PIER LUCIO;LATTUADA LUCIANO;UGGERI FULVIO;LUX GIOVANNA;SERLETI MICHELE;GABELLINI MILENA;TOURNIER HERVE |
分类号 |
A61K49/00;A61K49/06;A61K49/18;C07C229/16;C07C229/76;C07C233/47;C07C237/08;C07C237/10;C07C237/12;C07D257/02;C07F9/09;C07J41/00;(IPC1-7):C07C233/07 |
主分类号 |
A61K49/00 |
代理机构 |
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地址 |
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