| 摘要 |
<p>The invention concerns a method for performing a conversion of an amorphous material to a corresponding essentially crystalline material. At least partly amorphous material is spray dried using a feed solution which is a suspending medium in which said material is practically insoluble. The invention further concerns an inhalation formulation containing a pharmaceutically active agent, a carrier and optionally conventional excipients used in inhalation formulations. At least one of the components have been spray dried using a feed solution which is a suspending medium in which said component is practically insoluble, for converting the amorphous component into an essentially crystalline form. The amorphous component is e.g. lactose or salbutamol, and the suspending medium may be ethanol.</p> |
